BML-259

Product Name: BML-259
CAS No.: 267654-00-2
Chemical Name: BML-259
Synonyms: BML-259;CAY10554;Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]-;2-phenyl-N-(5-propan-2-yl-1,3-thiazol-2-yl)acetamide;BML-259,protein,p53,CDK,death,disease,neurotoxicity,cell,Inhibitor,inhibit,Cyclin dependent kinase,Alzheimer's
CBNumber: CB12450947
Molecular Formula: C14H16N2OS
Formula Weight: 260.35
MOL File: 267654-00-2.mol

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BML-259 Property

Melting point:: 150-152℃
storage temp.: RT
solubility: Soluble in DMSO (up to 25 mg/ml).
form: White solid.
color: white
Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SRP0704
Product name: BML-259
Purity: recombinant
Packaging: 25mg
Price: $341
Updated: 2024/03/01

Alfa Aesar

Product number: J67143
Product name: BML-259, 98%
Packaging: 5mg
Price: $139
Updated: 2023/06/20

Cayman Chemical

Product number: 10010301
Product name: CAY10554
Purity: ≥95%
Packaging: 5mg
Price: $64
Updated: 2024/03/01

Cayman Chemical

Product number: 10010301
Product name: CAY10554
Purity: ≥95%
Packaging: 10mg
Price: $119
Updated: 2024/03/01

Cayman Chemical

Product number: 10010301
Product name: CAY10554
Purity: ≥95%
Packaging: 25mg
Price: $280
Updated: 2024/03/01

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BML-259 Chemical Properties,Usage,Production

Description

BML-259 (267654-00-2) is a potent inhibitor of Cdk5/p25 (IC50 = 64 nM) and Cdk2 (IC50 = 98nM).1

Definition

ChEBI: 2-phenyl-N-(5-propan-2-yl-2-thiazolyl)acetamide is a member of acetamides.

References

1) Helal et al. (2004) Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer’s disease; Bioorg. Med. Chem. Lett. 14 5521

BML-259 Preparation Products And Raw materials

Raw materials

Preparation Products

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BML-259 Suppliers

China 35 United States 5 Global 40

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9926
Advantage: 65

Aladdin Scientific

Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 52927
Advantage: 58

267654-00-2, BML-259Related Search:

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BML-259

CAY10554

2-phenyl-N-(5-propan-2-yl-1,3-thiazol-2-yl)acetamide

Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]-

BML-259,protein,p53,CDK,death,disease,neurotoxicity,cell,Inhibitor,inhibit,Cyclin dependent kinase,Alzheimer's

267654-00-2